Prenatal supplements aim to cover elevated micronutrient needs during pregnancy and lactation. The critical nutrients are well-established; formulations should match clinical guidelines.
- Folate as 5-MTHF (600β800 mcg/day): Prevents neural tube defects. Methylated form preferred for women with MTHFR variants. Start before conception.
- Iron (27 mg/day RDA): Supports expanded blood volume. Gentler forms (bisglycinate, ferrous gluconate) reduce GI side effects.
- Choline (450 mg/day): Critical for fetal brain development. Often underdosed in prenatals.
- Omega-3 DHA (200β300 mg/day): Fetal brain and retinal development.
- Iodine (150β220 mcg/day): Thyroid function for maternal and fetal development.
- Vitamin D3 (1000β2000 IU/day): Bone development, immune function.
- Calcium (1000 mg/day total intake): Skeletal development. May come from diet.
- Folic acid (synthetic) rather than methylfolate (5-MTHF) β though folic acid is still better than nothing
- Vitamin A as retinol above 5000 IU (teratogenic at high doses; use beta-carotene instead)
- Herbal "pregnancy support" blends (most herbs are contraindicated in pregnancy)
- Prenatals with less than 200 mg DHA
- Iron doses above 45 mg daily without physician recommendation
Folate form, choline dose (often the weakest link in prenatals), DHA quantity, third-party testing for heavy metals and PCBs, and retinol safety. We prioritize products that include recommended but commonly-overlooked nutrients like choline and iodine.